Treatment of Cerebral Venous Thrombosis with Rivaroxaban

Stroke Unit, Emergency Department, San Camillo Hospital, Rome, Italy *Corresponding author: Anticoli S, MD, Stroke Unit, Emergency Department, San Camillo Hospital, Rome, Italy, E-mail: [email protected] Rec Date: Mar 07, 2016; Acc Date: Apr 27, 2016; Pub Date: May 05, 2016 Copyright: © 2016 Anticoli S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Citation: Anticoli S, Pezzella FR, Scifoni G, et al. Treatment of Cerebral Venous Thrombosis with Rivaroxaban. J Biomedical Sci. 2016, 5:3. Introduction Cerebral vein thrombosis (CVT) is a relatively uncommon type of stroke accounting for about 0.5% to 1% of all strokes [1,2]. The clinical presentation of CVT is highly variable and ranges from mild or non-specific symptoms of raised intracranial pressure such as headache or visual complains, to focal neurologic signs, generalized seizures or coma. Information about the natural history and prognosis of CVT is scarce and mostly based on studies of modest size [3]. The Rocket [1] trial documented that rivaroxabam, a novel oral anticoagulant, has a lower rate of most concerning bleeds: fatal bleeding and intra cranial haematoma compared to warfarin, which makes it particularly attractive for the treatment of CVT. Other authors [4,5] have published encouraging data on the use of rivaroxaban in CVT.